A. DERMIS

The dermis is a vascularized layer of connective tissue which supports the avascular epidermis.

Skin, Thick (H&E) [#47]- The dermis shows a strong eosinophilic staining reaction due to the presence of large amounts of collagen. Cells are relatively sparse in the dermis as indicated by the number of nuclei. Beneath the dermis is the hypodermis, which usually contains large amounts of fat tissue. The border between the dermis and hypodermis is often indistinct. The dermis is highly vascularized, and numerous capillaries are present in the region adjacent to the epidermis. Observe the dermal papilli which are finger-like projections of the dermis which interdigitate with the epidermal ridges. Examine those dermal papilli for the presence of Meissner's corpuscles which contain nerve endings sensitive to touch.

I n t e g u m e n t		3
	Slide Text A. DERMIS The dermis is a vascularized layer of connective tissue which supports the avascular epidermis. Skin, Thick (H&E) [#47]- The dermis shows a strong eosinophilic staining reaction due to the presence of large amounts of collagen. Cells are relatively sparse in the dermis as indicated by the number of nuclei. Beneath the dermis is the hypodermis, which usually contains large amounts of fat tissue. The border between the dermis and hypodermis is often indistinct. The dermis is highly vascularized, and numerous capillaries are present in the region adjacent to the epidermis. Observe the dermal papilli which are finger-like projections of the dermis which interdigitate with the epidermal ridges. Examine those dermal papilli for the presence of Meissner's corpuscles which contain nerve endings sensitive to touch.