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Colon (H&E) [#71]: Examine the inner lining of the colon. Note the presence of a thin band of smooth muscle upon which the inner lining of the colon rests. Follow this thin ring of smooth muscle around the colon and observe that there are discontinuities in the band that correspond to the presence of large numbers of lymphocytes. This is a lymphoid nodule (follicle) which may or may not contain a germinal center (arrow).