II. HEMATOPOIESIS

The red bone marrow of adult human bones is the major site of formation of erythrocytes, granulocytes, monocytes and platelets. (Remember, circulating lymphocytes are derived mainly from the mitotic activity of lymphoid organs). The percursor cells to these mature circulating forms are termed myeloid cells, when referred to as a group. You will examine a bone marrow smear and identify various types of myeloid cells. To simplify this exercise the following points should be kept in mind; 1) you will be unable to identify all cells in the smear, 2) make use of the descriptions of the cells in your atlas and text, and 3) granulocytic precursors outnumber erythroid precursors because granulocytes have a shorter lifespan than erythrocytes.

Bone Marrow, Human [#13, 14]- The most immediately obvious cell type will be the enormous megakaryocytes (this cell may be absent from some slides). The next largest cells to be seen are the stem cells. Use the following clues to identify the immature blood cells. Again, do not attempt to identify all the cells in the smear, but rather try to find good examples of each. The cell types you are expected to recognize are indicated by the asterisks.

H e m a t o l o g y		13
	Slide Text II. HEMATOPOIESIS The red bone marrow of adult human bones is the major site of formation of erythrocytes, granulocytes, monocytes and platelets. (Remember, circulating lymphocytes are derived mainly from the mitotic activity of lymphoid organs). The percursor cells to these mature circulating forms are termed myeloid cells, when referred to as a group. You will examine a bone marrow smear and identify various types of myeloid cells. To simplify this exercise the following points should be kept in mind; 1) you will be unable to identify all cells in the smear, 2) make use of the descriptions of the cells in your atlas and text, and 3) granulocytic precursors outnumber erythroid precursors because granulocytes have a shorter lifespan than erythrocytes. Bone Marrow, Human [#13, 14]- The most immediately obvious cell type will be the enormous megakaryocytes (this cell may be absent from some slides). The next largest cells to be seen are the stem cells. Use the following clues to identify the immature blood cells. Again, do not attempt to identify all the cells in the smear, but rather try to find good examples of each. The cell types you are expected to recognize are indicated by the asterisks.